Pyridines and derivatives

Aromatic organic compounds consist of an aromatic six-membered ring containing one nitrogen atom and five carbon atoms; includes compounds derived from pyridines.

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6,241 – 6,255 of 178,220 results

6,241

Medchemexpress LLC Recombinant human tropomyosin alpha-1 chain (His-tagged) | 50 UG

Recombinant human tropomyosin alpha-1 chain (His-tag) supplied lyophilized for research use. The product is full-length (284 amino acids), with an approximate molecular weight of 35 kDa, expressed in E. coli and intended for biochemical and cell biology applications; it is not validated for diagnostic or therapeutic use.

Full-length human sequence, 284 amino acids.
His tag facilitates purification and detection.
Expressed in E. coli for high-yield production.
Lyophilized from PBS with 10% glycerol for enhanced stability.
Low endotoxin level (<1 EU/μg) suitable for sensitive assays.
Store lyophilized at -20 °C; aliquot and freeze after reconstitution.

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6,242

Cayman Chemical CAY10498 Neurochemicals

The A1, A2A, A2B, and A3 adenosine receptors (ARs) are ubiquitous G protein-coupled receptors. The four AR subtypes have been implicated in several areas of therapeutic interest such as stroke and other ischemic conditions, as well as inflammation, neurodegenerative diseases, diabetes, and sleep regulation.{13281} A3 AR antagonists are of interest as therapeutic agents in glaucoma agents and inflammation. CAY10498 is a potent and selective A3 AR antagonist exhibiting a Ki of 37 nM with 60 and 200-fold selectivity over A1 and A2A adenosine receptors, respectively.{13281} CAY10498 is also a structural analog of reversine, a dedifferentiation agent of embryonic progenitor cells.{12913} However, no dedifferentiation effects or any connection between A3 AR antagonism and dedifferentiation have been demonstrated.

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6,243

Apexbio Technology LLC PhiKan 083 880813-36-5 5mg

PhiKan 083 (CAS 880813-36-5) is a small molecule that selectively binds to the Y220C mutant form of the tumor suppressor protein p53 This mutation creates a surface crevice that compromises protein stability leading to increased denaturation rates PhiKan 083 interacts with this cavity exhibiting an approximate dissociation constant (Kd) of 125 10 M and Ki near 150 M and stabilizes the mutant protein in vitro by significantly extending its half-life at physiological temperature By targeting a non-functional protein region PhiKan 083 serves as a lead compound for modulating mutant p53 stability and is commonly employed in studies investigating pharmacological rescue strategies for oncogenic p53 Y220C variants No in vivo or clinical data are currently available

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6,244

Medchemexpress LLC EBV EBNA3B (416-424) | 147138-29-2 | 99.52% | 1021.21 | 5 MG

EBV EBNA3B (416-424) is an HLA-A11-restricted peptide antigen derived from EBV EBNA3B protein.

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6,245

Medchemexpress LLC GFB-024 1mg | 1mg

GFB-024 is a CHO-expressed humanized antibody that targets CB1/CNR1 GFB-024 has a huIgG1 heavy chain and a hu light chain with a predicted molecular weight (MW) of 145 kDa The isotype control for GFB-024 can refer to Human IgG1 kappa Isotype Control (HY-P99001)

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6,246

Medchemexpress LLC Biphenyl-type kinesin-5 inhibitor | 1141768-04-8 | 99.6% | 50 MG

PVZB1194 is a biphenyl-type small-molecule inhibitor of Kinesin-5 ATPase that binds the α4/α6 site of the motor domain in a nucleotide-competitive manner and induces mitotic arrest with monopolar spindle formation.

High purity: 99.6% reported (99.64% listed).
Chemical formula: C13H9F4NO2S.
Molecular weight: 319.27 g/mol.
CAS number: 1141768-04-8.
Solubility: soluble in DMSO (250 mg/mL; may require ultrasonic).
Storage: powder typically stored at -20°C; in solution store at -80°C for long term.
Intended use: research reagent for studying mitosis and kinesin-5 function; not for human use.

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6,247

BIOHIPPO AAV-CRH-hM3D(Gq)-mCherry-WPREs

Recombinant adeno associated virus expressing hM3D(Gq) fused to mCherry under the CRH promoter with WPRE and hGH polyA elements. The Dre dependent configuration enables expression only after recombination, providing precise chemogenetic control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.

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6,248

Medchemexpress LLC Surufatinib (sulfatinib) | 1308672-74-3 | >98.0% | 1 MG

Sulfatinib (surufatinib) is a small-molecule tyrosine kinase inhibitor that selectively targets VEGFR1/2/3, FGFR1, and CSF1R. It is supplied as a high-purity analytical reference for research into angiogenesis and tumor signaling pathways.

Targets VEGFR1/2/3, FGFR1, and CSF1R with low-nanomolar potency.
High purity analytical standard (≥98%).
Molecular formula C24H28N6O3S and molecular weight 480.6 g·mol-1.
Solid powder formulation suitable for analytical and in vitro research.
Available in small quantities for laboratory use (e.g., 1 MG).

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6,249

Medchemexpress LLC CSF1R Mouse HEK293 50ug

The CSF1R protein is a tyrosine protein kinase receptor for CSF1 and IL34 and plays a critical regulatory role in hematopoietic cells especially mononuclear phagocytes Its effects span innate immunity inflammation osteoclast function skeletal development and fertility CSF1R Protein Mouse (HEK293 Fc) is the recombinant mouse-derived CSF1R protein expressed by HEK293 with C-hFc labeled tag

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6,250

BIOHIPPO AAV-GFAP(681)-hM3D(Gq)-mCherry-WPREs

Recombinant adeno associated virus expressing hM3D(Gq) fused to mCherry under the GFAP promoter with WPRE and hGH polyA elements. The Dre dependent configuration enables expression only after recombination, providing precise chemogenetic control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.

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6,251

Medchemexpress LLC DHH Mouse 100ug

DHH Protein Mouse is a single non-glycosylated polypeptide chain Desert hedgehog protein (DHH) is a member of the Hedgehog family which encodes signaling molecules that play an important role in regulating morphogenesis

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6,252

Cayman Chemical Erlotinib Inhibitors

An EGFR inhibitor (Ki = 2.7 nM); selective for EGFR over Src and Abl at 0.1 µM; induces caspase-3 and -7 activity in NCI H358 cells at 1 µM; reduces EGFR autophosphorylation in an HN-5 mouse xenograft model at 25 mg/kg

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6,253

Medchemexpress LLC Hexaflumuron | 86479-06-3 | MFCD01743935 | 99.7% | 25 MG

Hexaflumuron is an insect growth regulator (IGR) that inhibits chitin synthesis during insect molting. It is intended for research and analytical applications.

Targets insecticide.
Used in various research areas.
Applicable for research and analytical applications.
Inhibits chitin synthesis during insect molting.

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6,254

Medchemexpress LLC Danburstotug 1mg | 1mg

Danburstotug (IMC-001) is an IgG1-lambda anti-CD274 (PDL1 B7 homologue 1 B7H1) human monoclonal antibody Danburstotug also is immunostimulant and antineoplastic[1]

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6,255

Medchemexpress LLC PARP1-IN-11 | 2482484-87-5 | 99.4% | 296.28 | 100 MG

PARP1-IN-11 (compound 49) is a potent PARP1 inhibitor with an IC50 value of 0.082 μM. It demonstrates complete inhibition of PARP2 and substantially inhibits PARP3, TNKS1, and TNKS2.

Potent PARP1 inhibitor
IC50 value of 0.082 μM for PARP1
Completely inhibits PARP2
Substantially inhibits PARP3
Substantially inhibits TNKS1
Substantially inhibits TNKS2

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Pyridines and derivatives

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Medchemexpress LLC Recombinant human tropomyosin alpha-1 chain (His-tagged) | 50 UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Cayman Chemical CAY10498 Neurochemicals Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC PhiKan 083 880813-36-5 5mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC EBV EBNA3B (416-424) | 147138-29-2 | 99.52% | 1021.21 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC GFB-024 1mg | 1mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Biphenyl-type kinesin-5 inhibitor | 1141768-04-8 | 99.6% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

BIOHIPPO AAV-CRH-hM3D(Gq)-mCherry-WPREs Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Surufatinib (sulfatinib) | 1308672-74-3 | >98.0% | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC CSF1R Mouse HEK293 50ug Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

BIOHIPPO AAV-GFAP(681)-hM3D(Gq)-mCherry-WPREs Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC DHH Mouse 100ug Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Cayman Chemical Erlotinib Inhibitors Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Hexaflumuron | 86479-06-3 | MFCD01743935 | 99.7% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Danburstotug 1mg | 1mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC PARP1-IN-11 | 2482484-87-5 | 99.4% | 296.28 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More